In vivo cytotoxic effects of methanol extract of Convolvulus arvensis on 7-12-dimethyl benz(a)antheracene (DMBA) induced skin carcinogenesis

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Background: Melastoma malabathricum L. Smith (family Melastomaceae) is a shrub that has been used by the Malay practitioners of traditional medicine to treat various types of ailments. The present study aimed to determine the chemopreventive activity of methanol extract of M. malabathricum leaves (MEMM) using the standard 7,12dimethylbenz(α)anthracene (DMBA)/croton oil-induced mouse skin carcin...

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Chemopreventive activity of methanol extract of Melastoma malabathricum leaves in DMBA-induced mouse skin carcinogenesis.

BACKGROUND Melastoma malabathricum L. Smith (family Melastomaceae) is a shrub that has been used by the Malay practitioners of traditional medicine to treat various types of ailments. The present study aimed to determine the chemopreventive activity of methanol extract of M. malabathricum leaves (MEMM) using the standard 7,12-dimethylbenz(α)anthracene (DMBA)/croton oil-induced mouse skin carcin...

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Objective: Some species of Astragalus are used for the treatment of various types of cancer. The present study was designed to evaluate the anticancer potential of Astragalus ovinus extract (AOE) against DMBA-induced breast carcinoma in rats. Materials and Methods: The anti-tumor and antioxidant effects of AOE were evaluated against DMBA...

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ژورنال

عنوان ژورنال: African Journal of Pharmacy and Pharmacology

سال: 2015

ISSN: 1996-0816

DOI: 10.5897/ajpp2014.4165